منابع مشابه
Warfarin-related nephropathy modeled by nephron reduction and excessive anticoagulation.
An acute increase in international normalized ratio (INR) to >3.0 in patients with chronic kidney disease (CKD) can associate with an unexplained acute increase in serum creatinine and accelerated progression of CKD. A subset of these patients have renal tubular obstruction by casts of red blood cells, presumably the dominant mechanism of the acute kidney injury described as warfarin-related ne...
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Novel oral anticoagulants (NOAC) are a group of drugs recently approved for the treatment of patients at high risk of arterial or venous thrombosis. Unlike vitamin K antagonists, NOAC have a faster onset of action, less drug interactions and do not need frequent monitoring, making their prescription more convenient for physicians and patients. However, both classes of drugs have the potential f...
متن کاملRecognizing isolated IgG4-related nephropathy
IgG4-related tubulointerstitial nephritis is an uncommon cause of renal impairment. It has been associated with dysfunction in a number of other organs giving rise to the term IgG4-related systemic disease; organ involvement can occur metachronously, hence, making it more difficult to identify patients. The exact cause of this condition remains unknown. Here, we present a case of isolated renal...
متن کاملDabigatran-Related Nephropathy in a Patient with Undiagnosed IgA Nephropathy
Dabigatran is a direct thrombin inhibitor used as an alternative to warfarin for long term anticoagulation. Warfarin-related nephropathy is an increasingly recognized entity, but recent evidence suggests that dabigatran can cause a WRN-like syndrome. We describe a case of a biopsy-proven anticoagulant nephropathy related to dabigatran in a patient with IgA nephropathy and propose that, despite ...
متن کاملProthrombin complex concentrate-related thrombotic risk following anticoagulation reversal.
Dear Sirs, We read with interest the report of the meta-analysis performed by Dentali et al. on the adverse events after prothrombin complex concentrate (PCC) use for the emergency reversal of vitamin K antagonists (1). The authors identified a low incidence of thrombotic events and a non-significant difference between fourand three-factor PCCs at 1.8% and 0.7%, respectively. We do not wish to ...
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ژورنال
عنوان ژورنال: Journal of Thrombosis and Haemostasis
سال: 2016
ISSN: 1538-7933
DOI: 10.1111/jth.13229